Fildena: A Pharmaceutical Overview

Characteristic	Details
Active Ingredient	Sildenafil
Dosage Forms	50 mg, 100 mg
Route of Administration	Oral
Primary Use	Erectile Dysfunction
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Table of Contents

Chemical Structure

Sildenafil, the active ingredient in Fildena, possesses a complex chemical structure. It is a small molecule with the formula C22H30N6O4S. This includes various functional groups, each playing a role in its bioactivity. The core is a piperazine ring. Attached are phenyl and pyrimidine groups. These groups form the backbone of its molecular configuration. The presence of a sulfonyl group is pivotal for its function. This structure facilitates its binding to phosphodiesterase type 5 (PDE5).

Correct Use

Fildena, such as sildenafil 100 mg, must be consumed responsibly. Patients should adhere strictly to prescribed dosages. It is typically administered one hour before sexual activity. Avoid taking it more than once a day. Oral ingestion is preferred, with water. Food can affect absorption rates. Fatty meals delay its action. Patients should seek medical advice before use. This is especially true for those with cardiovascular issues. Always consult a healthcare professional.

FDA-Approved Indications

Fildena is FDA-approved for treating erectile dysfunction. It enhances erectile function by increasing blood flow. This is achieved through PDE5 inhibition. It is not indicated for use in women or children. Caution is advised in patients with underlying health conditions. Its efficacy in pulmonary arterial hypertension is also documented. However, it should only be used under medical supervision. Any off-label use is discouraged without professional guidance.

Fildena Interactions

Interactions with Fildena can be significant. Nitrate medications pose a risk of severe hypotension. Antihypertensives can amplify blood pressure-lowering effects. Alcohol consumption may exacerbate side effects. CYP3A4 inhibitors can affect metabolism rates. Grapefruit products may alter its efficacy. Patients should disclose all medications to their doctor. Understanding potential interactions is crucial. Safety and efficacy must remain priorities.

Toxicity

Fildena’s toxicity is dose-dependent. Overdosage may lead to severe adverse reactions. Symptoms include dizziness, vision changes, and priapism. Cardiovascular complications are a risk. Emergency medical attention is necessary in such cases. Standard dosages rarely cause toxicity. Monitoring is advised for patients with renal impairment. Animal studies indicate moderate toxicity levels. Human data remains a priority for assessing safety.

Is non-prescription Fildena available?

Fildena is not available over-the-counter. Prescription-only status ensures medical oversight. This guarantees patient safety and appropriate use. Unregulated purchases pose significant risks. Counterfeit products may lack efficacy and safety. Patients should consult healthcare professionals before use. Reliable sources ensure genuine and effective medication. The importance of adhering to prescription guidelines cannot be overstated.

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